There are many drugs in the World of Crusty, some triggering hyperactive responses, some making you see Weird Shit Man (original character do not steal), and some drugs can talk shit about you because they're absolute twats and you dry humped their mother last night.
Here is a list of available drugs for you to obtain:
Snort everything around you then you are good to go. Even tablecloth. Or tea leaves. TEA LEAVES.